evestnikРоссийский социально-гуманитарный журналRussian Social and Humanitarian Journal2224-0209State University of Education10.18384/2224-0209-2013-4-636evestnik-636Research ArticleБИОЛОГИЯРОЛЬ ФИЗИЧЕСКОЙ АКТИВНОСТИ В ПРОФИЛАКТИКЕ И КОРРЕКЦИИ СЕРДЕЧНО-СОСУДИСТЫХ ЗАБОЛЕВАНИЙ. ОБЗОР ЛИТЕРАТУРЫROLE OF PHYSICAL ACTIVITY IN PREVENTIVE MAINTENANCE AND TREATMENT OF CARDIOVASCULAR DISEASES. LITERATURE SURVEYГоловановС. А.GolovanovS. ..noemail@neicon.ruАрхиповР. Н.ArkhypovR. ..noemail@neicon.ruРасуловМ. М.RasulovM. ..noemail@neicon.ruАнохинаН. Д.AnokhinaN. ..noemail@neicon.ru2013301220130444Copyright © Голованов С.А., Архипов Р.Н., Расулов М.М., Анохина Н.Д., 20132013Голованов С.А., Архипов Р.Н., Расулов М.М., Анохина Н.Д.Golovanov S..., Arkhypov R..., Rasulov M..., Anokhina N...Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.evestnik-mgou.ru/jour/article/view/636

В обзорной статье приведены современные литературные данные о роли физической активности в профилактике и лечении сердечно-сосудистых заболеваний. Показано, что регулярная физическая активность оказывает существенный положительный эффект на здоровье и производительность труда. Эти эффекты легко предсказуемы, зависят от величины нагрузок, реализуемы для широкого круга лиц. Приведены сведения об изменениях уровней оксида азота, свободных радикалов и «гасителей» свободных радикалов в клетках, а также о молекулярных процессах в эндотелии и мышцах (таких, как высокий уровень метаболизма фосфатов и сниженная экспрессия NAD(P)H оксидазы). Эти изменения зависят от интенсивности физических упражнений, демонстрирующих снижение оксидативного стресса при умеренной физической активности. Представлены рекомендации по программированию упражнений для лиц, страдающих различными заболеваниями сердечно-сосудистой системы.

The review gives modern scientific data on the role of physical activity in preventive maintenance and treatment of cardiovascular diseases. It is shown that regular physical activity influences health and labor productivity positively. These effects are easily predicted, depend on the amount of physical activity, and are suitable for a wide range of persons. The authors present the data on the changes of the NO levels, free radical levels and the inhibitors of free radicals in cells. Besides, there is information about the molecular processes in endothelium and muscles (such as high level of metabolism of phosphates and lowered expression of NAD(P)H oxidaze), depending on the intensity of the physical exercises which show the decrease of oxidative stress at moderate physical activity. Recommendations on programming the exercises for the persons suffering from various cardiovascular diseases are presented.

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The authors declare that there are no conflicts of interest present.